5HGQ

Loa loa Lysyl-tRNA synthetase in complex with Cladosporin.

Summary for 5HGQ

• Entry DOI: 10.2210/pdb5hgq/pdb
• Descriptor: Lysine--tRNA ligase, LYSINE, cladosporin, ... (5 entities in total)
• Functional Keywords: cladosporin, lysine-trna synthetase, loa loa, helminth parasites, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• Biological source: Loa loa (Eye worm)
• Total number of polymer chains: 4
• Total formula weight: 242159.13

Authors

Sharma, A.,Sharma, M.,Yogavel, M.,Sharma, A. (deposition date: 2016-01-08, release date: 2016-10-26, Last modification date: 2023-11-08)

• Primary citation: Sharma, A.,Sharma, M.,Yogavel, M.,Sharma, A.; Protein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis; PLoS Negl Trop Dis, 10:e0005084-e0005084, 2016; PubMed: 27806050; DOI: 10.1371/journal.pntd.0005084

Experimental method

X-RAY DIFFRACTION (3.283 Å)