5HGQ
Loa loa Lysyl-tRNA synthetase in complex with Cladosporin.
Summary for 5HGQ
Entry DOI | 10.2210/pdb5hgq/pdb |
Descriptor | Lysine--tRNA ligase, LYSINE, cladosporin, ... (5 entities in total) |
Functional Keywords | cladosporin, lysine-trna synthetase, loa loa, helminth parasites, ligase-ligase inhibitor complex, ligase/ligase inhibitor |
Biological source | Loa loa (Eye worm) |
Total number of polymer chains | 4 |
Total formula weight | 242159.13 |
Authors | Sharma, A.,Sharma, M.,Yogavel, M.,Sharma, A. (deposition date: 2016-01-08, release date: 2016-10-26, Last modification date: 2023-11-08) |
Primary citation | Sharma, A.,Sharma, M.,Yogavel, M.,Sharma, A. Protein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis PLoS Negl Trop Dis, 10:e0005084-e0005084, 2016 Cited by PubMed: 27806050DOI: 10.1371/journal.pntd.0005084 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.283 Å) |
Structure validation
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