5HGQ

Loa loa Lysyl-tRNA synthetase in complex with Cladosporin.

5HGQ の概要

• エントリーDOI: 10.2210/pdb5hgq/pdb
• 分子名称: Lysine--tRNA ligase, LYSINE, cladosporin, ... (5 entities in total)
• 機能のキーワード: cladosporin, lysine-trna synthetase, loa loa, helminth parasites, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• 由来する生物種: Loa loa (Eye worm)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 242159.13

構造登録者

Sharma, A.,Sharma, M.,Yogavel, M.,Sharma, A. (登録日: 2016-01-08, 公開日: 2016-10-26, 最終更新日: 2023-11-08)

• 主引用文献: Sharma, A.,Sharma, M.,Yogavel, M.,Sharma, A.; Protein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis; PLoS Negl Trop Dis, 10:e0005084-e0005084, 2016; PubMed: 27806050; DOI: 10.1371/journal.pntd.0005084

実験手法

X-RAY DIFFRACTION (3.283 Å)