5HGJ
Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition
Summary for 5HGJ
Entry DOI | 10.2210/pdb5hgj/pdb |
Descriptor | Integrin alpha-1, CALCIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | integrin, signaling, rossman, i-domain, cell adhesion |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 43921.21 |
Authors | Brown, K.L.,Banerjee, S.,Feigley, A.,Abe, H.,Blackwell, T.,Zent, R.,Pozzi, A.,Hudson, B.H. (deposition date: 2016-01-08, release date: 2017-04-12, Last modification date: 2024-03-06) |
Primary citation | Brown, K.L.,Banerjee, S.,Feigley, A.,Abe, H.,Blackwell, T.S.,Pozzi, A.,Hudson, B.G.,Zent, R. Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains. Sci Rep, 8:2916-2916, 2018 Cited by PubMed: 29440721DOI: 10.1038/s41598-018-21231-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.399 Å) |
Structure validation
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