5HGJ

Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition

5HGJ の概要

• エントリーDOI: 10.2210/pdb5hgj/pdb
• 分子名称: Integrin alpha-1, CALCIUM ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: integrin, signaling, rossman, i-domain, cell adhesion
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43921.21

構造登録者

Brown, K.L.,Banerjee, S.,Feigley, A.,Abe, H.,Blackwell, T.,Zent, R.,Pozzi, A.,Hudson, B.H. (登録日: 2016-01-08, 公開日: 2017-04-12, 最終更新日: 2024-03-06)

• 主引用文献: Brown, K.L.,Banerjee, S.,Feigley, A.,Abe, H.,Blackwell, T.S.,Pozzi, A.,Hudson, B.G.,Zent, R.; Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains.; Sci Rep, 8:2916-2916, 2018; PubMed: 29440721; DOI: 10.1038/s41598-018-21231-1

実験手法

X-RAY DIFFRACTION (1.399 Å)