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5HBM

Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase

5HBM の概要
エントリーDOI10.2210/pdb5hbm/pdb
分子名称Reverse transcriptase/ribonuclease H, p51 RT, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, ... (6 entities in total)
機能のキーワードtransferase, hydrolase, inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor
由来する生物種Human immunodeficiency virus type 1 BH10 (HIV-1)
詳細
タンパク質・核酸の鎖数2
化学式量合計114698.13
構造登録者
Kirby, K.A.,Sarafianos, S.G. (登録日: 2015-12-31, 公開日: 2016-02-24, 最終更新日: 2023-09-27)
主引用文献Kirby, K.A.,Sarafianos, S.G.
Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase
To Be Published,
実験手法
X-RAY DIFFRACTION (3.043 Å)
構造検証レポート
Validation report summary of 5hbm
検証レポート(詳細版)ダウンロードをダウンロード

217705

件を2024-03-27に公開中

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