5HBM

Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase

5HBM の概要

• エントリーDOI: 10.2210/pdb5hbm/pdb
• 分子名称: Reverse transcriptase/ribonuclease H, p51 RT, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, ... (6 entities in total)
• 機能のキーワード: transferase, hydrolase, inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Human immunodeficiency virus type 1 BH10 (HIV-1); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114698.13

構造登録者

Kirby, K.A.,Sarafianos, S.G. (登録日: 2015-12-31, 公開日: 2016-02-24, 最終更新日: 2023-09-27)

• 主引用文献: Kirby, K.A.,Sarafianos, S.G.; Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase; To Be Published,

実験手法

X-RAY DIFFRACTION (3.043 Å)