5H5B

Citrate ion bound crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 5H5B

Related2PBR 5H56 5H5K
DescriptorThymidylate kinase, CITRATE ANION (3 entities in total)
Functional Keywordskinase, transferase, rossmann fold, product-bound
Biological sourceAquifex aeolicus (strain VF5)
Total number of polymer chains2
Total molecular weight45184.12
Authors
Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2016-11-05, release date: 2017-06-28, Last modification date: 2017-08-30)
Primary citation
Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K.
Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate
FEBS J., 284:2527-2544, 2017
PubMed: 28627020 (PDB entries with the same primary citation)
DOI: 10.1111/febs.14140
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27510.3%0.7%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution