5H1L

Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment

Summary for 5H1L

• Entry DOI: 10.2210/pdb5h1l/pdb
• Related: 5H1J 5H1K 5H1M
• Descriptor: Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3'), GLYCEROL, ... (4 entities in total)
• Functional Keywords: wd repeat, gemin5, smn, u4 snrna, rna binding, splicing-rna complex, splicing/rna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus, nucleoplasm : Q8TEQ6
• Total number of polymer chains: 2
• Total formula weight: 83680.49

Authors

Jin, W.,Wang, Y.,Liu, C.P.,Yang, N.,Jin, M.,Cong, Y.,Wang, M.,Xu, R.M. (deposition date: 2016-10-10, release date: 2016-11-23, Last modification date: 2023-11-08)

• Primary citation: Jin, W.,Wang, Y.,Liu, C.P.,Yang, N.,Jin, M.,Cong, Y.,Wang, M.,Xu, R.M.; Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5; Genes Dev., 30:2391-2403, 2016; PubMed: 27881601; DOI: 10.1101/gad.291377.116

Experimental method

X-RAY DIFFRACTION (2.1 Å)