5GWY
Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design
Summary for 5GWY
Entry DOI | 10.2210/pdb5gwy/pdb |
Related PRD ID | PRD_002214 |
Descriptor | main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE (3 entities in total) |
Functional Keywords | hcov-nl63, main protease, inhibitor, complex, drug design, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human coronavirus NL63 (HCoV-NL63) More |
Total number of polymer chains | 4 |
Total formula weight | 67710.74 |
Authors | |
Primary citation | Wang, F.,Chen, C.,Tan, W.,Yang, K.,Yang, H. Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design. Sci Rep, 6:22677-22677, 2016 Cited by PubMed: 26948040DOI: 10.1038/srep22677 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.852 Å) |
Structure validation
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