5GJ4
Structure of NS2B-NS3 Protease from Zika Virus caught after self-cleavage
Summary for 5GJ4
Entry DOI | 10.2210/pdb5gj4/pdb |
Descriptor | Serine protease subunit NS2B, Serine protease NS3, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | zika virus protease, antiviral drug discovery, hydrolase |
Biological source | Zika virus (strain Mr 766) (ZIKV) More |
Cellular location | Virion membrane ; Multi-pass membrane protein : A0A142IX72 A0A142IX72 |
Total number of polymer chains | 8 |
Total formula weight | 102878.54 |
Authors | Phoo, W.W.,Li, Y. (deposition date: 2016-06-27, release date: 2016-10-26, Last modification date: 2023-11-08) |
Primary citation | Phoo, W.W.,Li, Y.,Zhang, Z.,Lee, M.Y.,Loh, Y.R.,Tan, Y.B.,Ng, E.Y.,Lescar, J.,Kang, C.,Luo, D. Structure of the NS2B-NS3 protease from Zika virus after self-cleavage. Nat Commun, 7:13410-13410, 2016 Cited by PubMed: 27845325DOI: 10.1038/ncomms13410 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.839 Å) |
Structure validation
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