5GJ4
Structure of NS2B-NS3 Protease from Zika Virus caught after self-cleavage
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0044423 | cellular_component | virion component |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003724 | molecular_function | RNA helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0044423 | cellular_component | virion component |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003724 | molecular_function | RNA helicase activity |
| D | 0005524 | molecular_function | ATP binding |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0044423 | cellular_component | virion component |
| F | 0003723 | molecular_function | RNA binding |
| F | 0003724 | molecular_function | RNA helicase activity |
| F | 0005524 | molecular_function | ATP binding |
| G | 0004252 | molecular_function | serine-type endopeptidase activity |
| G | 0044423 | cellular_component | virion component |
| H | 0003723 | molecular_function | RNA binding |
| H | 0003724 | molecular_function | RNA helicase activity |
| H | 0005524 | molecular_function | ATP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 2001 |
| Chain | Residue |
| B | ARG105 |
| B | ALA106 |
| E | HOH219 |
| F | ALA106 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 201 |
| Chain | Residue |
| C | HOH213 |
| D | ARG105 |
| D | ALA106 |
| H | ALA106 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 88 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"PubMed","id":"29080786","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29526431","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
