5GIK
Modulation of the affinity of a HIV-1 capsid-directed ankyrin towards its viral target through critical amino acid editing
Summary for 5GIK
Entry DOI | 10.2210/pdb5gik/pdb |
Descriptor | Artificial ankyrin repeat protein_Ank(GAG)1D4 mutant -S45Y, GLYCEROL (3 entities in total) |
Functional Keywords | darpins, designed ankyrin repeat, protein binding |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 16948.08 |
Authors | Chuankhayan, P.,Saoin, S.,Wisitponchai, T.,Intachai, K.,Chupradit, K.,Moonmuang, S.,Kitidee, K.,Nangola, S.,Sanghiran, L.V.,Hong, S.S.,Boulanger, P.,Tayapiwatana, C.,Chen, C.J. (deposition date: 2016-06-24, release date: 2017-06-28, Last modification date: 2024-03-20) |
Primary citation | Chuankhayan, P.,Saoin, S.,Wisitponchai, T.,Intachai, K.,Chupradit, K.,Moonmuang, S.,Kitidee, K.,Nangola, S.,Sanghiran, L.V.,Hong, S.S.,Boulanger, P.,Tayapiwatana, C.,Chen, C.J. Modulation of the affinity of a HIV-1 capsid-directed ankyrintowards its viral target through critical amino acid editing To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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