5GIK

Modulation of the affinity of a HIV-1 capsid-directed ankyrin towards its viral target through critical amino acid editing

Summary for 5GIK

• Entry DOI: 10.2210/pdb5gik/pdb
• Descriptor: Artificial ankyrin repeat protein_Ank(GAG)1D4 mutant -S45Y, GLYCEROL (3 entities in total)
• Functional Keywords: darpins, designed ankyrin repeat, protein binding
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 16948.08

Authors

Chuankhayan, P.,Saoin, S.,Wisitponchai, T.,Intachai, K.,Chupradit, K.,Moonmuang, S.,Kitidee, K.,Nangola, S.,Sanghiran, L.V.,Hong, S.S.,Boulanger, P.,Tayapiwatana, C.,Chen, C.J. (deposition date: 2016-06-24, release date: 2017-06-28, Last modification date: 2024-03-20)

• Primary citation: Chuankhayan, P.,Saoin, S.,Wisitponchai, T.,Intachai, K.,Chupradit, K.,Moonmuang, S.,Kitidee, K.,Nangola, S.,Sanghiran, L.V.,Hong, S.S.,Boulanger, P.,Tayapiwatana, C.,Chen, C.J.; Modulation of the affinity of a HIV-1 capsid-directed ankyrintowards its viral target through critical amino acid editing; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.49 Å)