5GI9
Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-Tryptamine
Summary for 5GI9
Entry DOI | 10.2210/pdb5gi9/pdb |
Related | 5GI5 5GI6 5GI7 5GI8 |
Descriptor | Dopamine N-acetyltransferase, COENZYME A, ~{N}-[2-(1~{H}-indol-3-yl)ethyl]ethanamide, ... (5 entities in total) |
Functional Keywords | dopamine n-acetyltransferase(dat), gcn5-related n-acetyltransferase(gnat), arylalkylamine n-acetyltransferase(aanat), order bi-bi sequential mechanism, transferase |
Biological source | Drosophila melanogaster (Fruit fly) |
Total number of polymer chains | 1 |
Total formula weight | 25766.32 |
Authors | Yang, Y.C.,Lin, S.J.,Cheng, K.C.,Cheng, H.C.,Lyu, P.C. (deposition date: 2016-06-22, release date: 2017-07-05, Last modification date: 2024-03-20) |
Primary citation | Wu, C.Y.,Hu, I.C.,Yang, Y.C.,Ding, W.C.,Lai, C.H.,Lee, Y.Z.,Liu, Y.C.,Cheng, H.C.,Lyu, P.C. An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase. Commun Biol, 3:441-441, 2020 Cited by PubMed: 32796911DOI: 10.1038/s42003-020-01177-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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