5GI7

Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-phenylethylamine

Summary for 5GI7

Entry DOI	10.2210/pdb5gi7/pdb
Related	5GI5 5GI6 5GI8 5GI9
Descriptor	Dopamine N-acetyltransferase, COENZYME A, N-(2-phenylethyl)acetamide, ... (5 entities in total)
Functional Keywords	dopamine n-acetyltransferase(dat), gcn5-related n-acetyltransferase(gnat), arylalkylamine n-acetyltransferase(aanat), order bi-bi sequential mechanism, transferase
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	1
Total formula weight	25688.25
Authors	Yang, Y.C.,Lin, S.J.,Cheng, K.C.,Cheng, H.C.,Lyu, P.C. (deposition date: 2016-06-22, release date: 2017-07-05, Last modification date: 2024-03-20)
Primary citation	Wu, C.Y.,Hu, I.C.,Yang, Y.C.,Ding, W.C.,Lai, C.H.,Lee, Y.Z.,Liu, Y.C.,Cheng, H.C.,Lyu, P.C. An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase. Commun Biol, 3:441-441, 2020 Cited by PubMed: 32796911 DOI: 10.1038/s42003-020-01177-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.201 Å)

Structure validation