5GHW
Crystal structure of broad neutralizing antibody 10E8 with long epitope bound
Summary for 5GHW
Entry DOI | 10.2210/pdb5ghw/pdb |
Descriptor | FAB 10E8 HEAVY CHAIN, FAB 10E8 LIGHT CHAIN, Endogenous retrovirus group K member 8 Env polyprotein, ... (5 entities in total) |
Functional Keywords | broad neutralizing antibody, recombinant fab, epitope, immune system, hiv-1, viral membrane |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 54089.79 |
Authors | Caaveiro, J.M.M.,Rujas, E.,Morante, K.,Nieva, J.L.,Tsumoto, K. (deposition date: 2016-06-21, release date: 2016-11-23, Last modification date: 2023-11-08) |
Primary citation | Rujas, E.,Caaveiro, J.M.,Partida-Hanon, A.,Gulzar, N.,Morante, K.,Apellaniz, B.,Garcia-Porras, M.,Bruix, M.,Tsumoto, K.,Scott, J.K.,Jimenez, M.A.,Nieva, J.L. Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface Sci Rep, 6:38177-38177, 2016 Cited by PubMed: 27905530DOI: 10.1038/srep38177 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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