5G43
Ligand complex of RORg LBD
Summary for 5G43
Entry DOI | 10.2210/pdb5g43/pdb |
Related | 5G42 5G44 5G45 5G46 |
Descriptor | NUCLEAR RECEPTOR ROR-GAMMA, RORG, 2-(1-PIPERIDINYL)-1,3-THIAZOL-4-AMINE, ... (4 entities in total) |
Functional Keywords | dna binding protein, rorg ligand, fragment screen, structure-based design, simultaneous binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus : P51449 |
Total number of polymer chains | 2 |
Total formula weight | 32577.46 |
Authors | Xue, Y.,Guo, H.,Hillertz, P. (deposition date: 2016-05-04, release date: 2016-08-03, Last modification date: 2024-05-08) |
Primary citation | Xue, Y.,Guo, H.,Hillertz, P. Fragment Screening of Rorgammat Using Cocktail Crystallography: Identification of Simultaneous Binding of Multiple Fragments. Chemmedchem, 11:1881-, 2016 Cited by PubMed: 27432277DOI: 10.1002/CMDC.201600242 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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