5G3R

Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine and L-Ala-1,6-anhydroMurNAc

Summary for 5G3R

Entry DOI	10.2210/pdb5g3r/pdb
Descriptor	, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[[(2R)-2-[[(1R,2S,3R,4R,5R)-4-acetamido-2-oxidanyl-6,8-dioxabicyclo[3.2.1]octan-3-yl]oxy]propanoyl]amino]propanamide, ... (5 entities in total)
Functional Keywords	hydrolase, cell-wall recycling, antibiotic resistance, glycoside hydrolase, n-acetylglucosaminidase, beta-hexosaminidase, peptidoglycan
Biological source	PSEUDOMONAS AERUGINOSA
Cellular location	Cytoplasm : Q9HZK0
Total number of polymer chains	2
Total formula weight	77980.70
Authors	Acebron, I.,Artola-Recolons, C.,Mahasenan, K.,Mobashery, S.,Hermoso, J.A. (deposition date: 2016-04-30, release date: 2017-05-17, Last modification date: 2020-07-29)
Primary citation	Acebron, I.,Mahasenan, K.V.,De Benedetti, S.,Lee, M.,Artola-Recolons, C.,Hesek, D.,Wang, H.,Hermoso, J.A.,Mobashery, S. Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa. J. Am. Chem. Soc., 139:6795-6798, 2017 Cited by PubMed: 28482153 DOI: 10.1021/jacs.7b01626 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation