5FZY

CRYSTAL STRUCTURE OF N19D POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR OF SERINE AND ASPARTIC PROTEASES IN SPACE GROUP C2221 AND PH 3.5

Summary for 5FZY

Related5FZU 5FZZ 5G00
DescriptorKTI-A PROTEIN (2 entities in total)
Functional Keywordshydrolase, sti-kunitz inhibitor, aspartic proteases, serine proteases, protease inhibitor, bi-functional protease inhibitor, hydrolase inhibitor, kunitz-type inhibitor
Biological sourceSOLANUM TUBEROSUM (POTATO)
Total number of polymer chains2
Total molecular weight41054.98
Authors
Guerra, Y.,Rudino-Pinera, E. (deposition date: 2016-03-15, release date: 2016-07-06, Last modification date: 2017-03-15)
Primary citation
Guerra, Y.,Valiente, P.A.,Pons, T.,Berry, C.,Rudino-Pinera, E.
Structures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: Could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop?
J. Struct. Biol., 195:259-271, 2016
PubMed: 27329566 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2016.06.014
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.47 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27580.3%4.0%2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution