5FWE

JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE

5FWE の概要

• エントリーDOI: 10.2210/pdb5fwe/pdb
• 分子名称: LYSINE-SPECIFIC DEMETHYLASE 4A, SYNTHETIC PEPTIDE, NICKEL (II) ION, ... (8 entities in total)
• 機能のキーワード: jmjd2a, oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, double-stranded beta helix, dsbh, facial triad, demethylase, histone, jmjc domain, metal binding protein, epigenetic and transcription regulation, chromatin regulator, hydroxylation
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 91992.96

構造登録者

Chowdhury, R.,Walport, L.J.,Schofield, C.J. (登録日: 2016-02-15, 公開日: 2016-04-06, 最終更新日: 2024-01-10)

• 主引用文献: Walport, L.J.,Hopkinson, R.J.,Chowdhury, R.,Schiller, R.,Ge, W.,Kawamura, A.,Schofield, C.J.; Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases.; Nat.Commun., 7:11974-, 2016; PubMed: 27337104; DOI: 10.1038/NCOMMS11974

実験手法

X-RAY DIFFRACTION (2.05 Å)