5FV3

Crystal structure of human JARID1B construct c2 in complex with N- Oxalylglycine.

Summary for 5FV3

• Entry DOI: 10.2210/pdb5fv3/pdb
• Related: 5FUP
• Descriptor: LYSINE-SPECIFIC DEMETHYLASE 5B, LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, DIMETHYL SULFOXIDE, ... (9 entities in total)
• Functional Keywords: oxidoreductase, jarid1b, plu1
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus : Q9UGL1
• Total number of polymer chains: 1
• Total formula weight: 57057.85

Authors

Nowak, R.,Srikannathasan, V.,Johansson, C.,Gileadi, C.,Kupinska, K.,Strain-Damerell, C.,Szykowska, A.,Talon, R.,von Delft, F.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Oppermann, U. (deposition date: 2016-02-02, release date: 2016-02-17, Last modification date: 2024-01-10)

• Primary citation: Johansson, C.,Velupillai, S.,Tumber, A.,Szykowska, A.,Hookway, E.S.,Nowak, R.P.,Strain-Damerell, C.,Gileadi, C.,Philpott, M.,Burgess-Brown, N.,Wu, N.,Kopec, J.,Nuzzi, A.,Steuber, H.,Egner, U.,Badock, V.,Munro, S.,Lathangue, N.B.,Westaway, S.,Brown, J.,Athanasou, N.,Prinjha, R.,Brennan, P.E.,Oppermann, U.; Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.; Nat.Chem.Biol., 12:539-, 2016; PubMed: 27214403; DOI: 10.1038/NCHEMBIO.2087

Experimental method

X-RAY DIFFRACTION (2.37 Å)