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5FV3

Crystal structure of human JARID1B construct c2 in complex with N- Oxalylglycine.

Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 1754
ChainResidue
ACYS692
ACYS695
ACYS715
AHIS718

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE DMS A 1755
ChainResidue
AGLU631
ALYS635
AGLU683
ATYR736
AHOH2044

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE DMS A 1756
ChainResidue
ATRP486
ATYR488
AVAL600
AASN601
AOGA1770
AHOH2054

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MN A 1757
ChainResidue
AHIS499
AGLU501
AHIS587
AOGA1770
AHOH2054

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MN A 1758
ChainResidue
AHIS622
AHIS718
AHOH2110

site_idAC6
Number of Residues13
DetailsBINDING SITE FOR RESIDUE EPE A 1759
ChainResidue
AILE500
ATRP504
ALEU541
APHE542
ALEU552
AVAL553
ATYR586
AHIS617
ATYR618
AARG623
AHOH2051
AHOH2057
AHOH2063

site_idAC7
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1760
ChainResidue
AASP630
ACYS699
APHE700
AMET701
ASER702
AEDO1762
AHOH2079

site_idAC8
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1761
ChainResidue
AARG666
ALEU732
ATYR734
ATHR737
AHOH2091

site_idAC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1762
ChainResidue
AARG612
AASP630
AMET658
AGLU662
AEDO1760

site_idBC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 1763
ChainResidue
APRO30
AVAL568

site_idBC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1764
ChainResidue
AASP688
AGLU689
AARG690
AGLN691
AVAL693
AGLY711
ALEU713

site_idBC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO A 1765
ChainResidue
AGLY524
AARG584
AHOH2120

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1766
ChainResidue
AARG670
AVAL674
AILE675
AHOH2090
AHOH2093

site_idBC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 1767
ChainResidue
ATRP70
ASER457

site_idBC6
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 1768
ChainResidue
ATYR425
ATYR488
ASER494
ALYS517
AASN591
AOGA1770
AHOH2047

site_idBC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CL A 1769
ChainResidue
ALEU90
AASN91
ALEU413
ATHR416
AGLU419
AHOH2020

site_idBC8
Number of Residues14
DetailsBINDING SITE FOR RESIDUE OGA A 1770
ChainResidue
ATYR488
APHE496
AHIS499
AGLU501
ASER507
AASN509
ALYS517
ATRP519
AHIS587
AALA599
ADMS1756
AMN1757
AEDO1768
AHOH2054

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues52
DetailsZN_FING: C5HC2 => ECO:0000269|PubMed:26741168, ECO:0000269|PubMed:27214403, ECO:0000269|PubMed:28262558
ChainResidueDetails
ACYS692-MET744

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P29375
ChainResidueDetails
ATYR425
ASER507
AASN509
ALYS517

site_idSWS_FT_FI3
Number of Residues3
DetailsBINDING: BINDING => ECO:0000305|PubMed:26741168, ECO:0000305|PubMed:27214403, ECO:0000305|PubMed:28262558
ChainResidueDetails
AHIS499
AGLU501
AHIS587

site_idSWS_FT_FI4
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS769

226707

PDB entries from 2024-10-30

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