5FU8

Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

Summary for 5FU8

• Entry DOI: 10.2210/pdb5fu8/pdb
• Descriptor: GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, N-(6-amino-1-(4-bromo-3-methylbenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzenesulfonamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (5 entities in total)
• Functional Keywords: thymidylyl, transferase, allosteric, inhibitor, pseudomonas
• Biological source: PSEUDOMONAS AERUGINOSA
• Total number of polymer chains: 4
• Total formula weight: 137496.64

Authors

Alphey, M.S.,Tran, F.,Westwood, N.J.,Naismith, J.H. (deposition date: 2016-01-21, release date: 2017-02-22, Last modification date: 2024-01-10)

• Primary citation: Tran, F.,Alphey, M.S.,Westwood, N.J.,Naismith, J.H.; Allosteric Competitive Inhibitors of the Glucose-1-Phosphate Thymidylyltransferase (Rmla) from Pseudomonas Aeruginosa.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)