5FS6

Crystal structure of the V243L mutant of human apoptosis inducing factor

Summary for 5FS6

Entry DOI	10.2210/pdb5fs6/pdb
Related	5FS7 5FS8 5FS9
Descriptor	APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL, FLAVIN-ADENINE DINUCLEOTIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	oxidoreductase, mitochondria, flavoprotein
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Mitochondrion intermembrane space. Isoform 3: Mitochondrion intermembrane space . Isoform 5: Cytoplasm : O95831
Total number of polymer chains	2
Total formula weight	114321.21
Authors	Sevrioukova, I. (deposition date: 2015-12-30, release date: 2016-05-11, Last modification date: 2024-01-10)
Primary citation	Sevrioukova, I. Structure/Function Relations in Aifm1 Variants Associated with Neurodegenerative Disorders J.Mol.Biol., 428:3650-, 2016 Cited by PubMed: 27178839 DOI: 10.1016/J.JMB.2016.05.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation