5FPP
Structure of a pre-reaction ternary complex between sarin- acetylcholinesterase and HI-6
Summary for 5FPP
| Entry DOI | 10.2210/pdb5fpp/pdb |
| Related | 5FOQ 5FPQ |
| Descriptor | ACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... (7 entities in total) |
| Functional Keywords | hydrolase, sarin, hi-6, qm, density functional theory calculations, michaelis complex. |
| Biological source | MUS MUSCULUS (HOUSE MOUSE) |
| Total number of polymer chains | 2 |
| Total formula weight | 122176.65 |
| Authors | Allgardsson, A.,Berg, L.,Akfur, C.,Hornberg, A.,Worek, F.,Linusson, A.,Ekstrom, F. (deposition date: 2015-12-02, release date: 2016-05-11, Last modification date: 2024-01-10) |
| Primary citation | Allgardsson, A.,Berg, L.,Akfur, C.,Hornberg, A.,Worek, F.,Linusson, A.,Ekstrom, F.J. Structure of a Prereaction Complex between the Nerve Agent Sarin, its Biological Target Acetylcholinesterase, and the Antidote Hi-6. Proc.Natl.Acad.Sci.USA, 113:5514-, 2016 Cited by PubMed: 27140636DOI: 10.1073/PNAS.1523362113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report
