5FNK

Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination

Summary for 5FNK

Entry DOI	10.2210/pdb5fnk/pdb
Related	5FNG 5FNH 5FNI 5FNJ 5FNL 5FNM
Descriptor	CARBONIC ANHYDRASE 2, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywords	lyase, fragments, carbonic anhydrase, metalloprotein
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	29755.69
Authors	Woods, L.A.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.A. (deposition date: 2015-11-15, release date: 2016-03-02, Last modification date: 2024-01-10)
Primary citation	Woods, L.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S. Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59:2192-, 2016 Cited by PubMed: 26882437 DOI: 10.1021/ACS.JMEDCHEM.5B01940 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation