5FLS
Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination
Summary for 5FLS
Entry DOI | 10.2210/pdb5fls/pdb |
Related | 5FLO 5FLP 5FLQ 5FLR 5FLT |
Descriptor | CARBONIC ANHYDRASE 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | lyase, fragments, metalloprotein |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 29629.23 |
Authors | Woods, L.A.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.A. (deposition date: 2015-10-28, release date: 2016-03-02, Last modification date: 2024-01-10) |
Primary citation | Woods, L.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S. Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59:2192-, 2016 Cited by PubMed: 26882437DOI: 10.1021/ACS.JMEDCHEM.5B01940 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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