5FL6
Three dimensional structure of human carbonic anhydrase IX in complex with 5-(1-(4-Methylphenyl)-1H-1,2,3-triazol-4-yl)thiophene-2- sulfonamide
Summary for 5FL6
Entry DOI | 10.2210/pdb5fl6/pdb |
Related | 5FL4 5FL5 |
Descriptor | CARBONIC ANHYDRASE IX, 5-[1-(4-methylphenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide, ZINC ION, ... (6 entities in total) |
Functional Keywords | lyase, carbonic anhydrase ix, carbonic anhydrase 9, ca ix, ca 9 |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 114722.41 |
Authors | Leitans, J.,Tars, K.,Zalubovskis, R. (deposition date: 2015-10-21, release date: 2015-11-11, Last modification date: 2024-01-10) |
Primary citation | Leitans, J.,Kazaks, A.,Balode, A.,Ivanova, J.,Zalubovskis, R.,Supuran, C.T.,Tars, K. An Efficient Expression and Crystallization System of the Cancer Asociated Carbonic Anhydrase Isoform Ix. J.Med.Chem., 58:9004-, 2015 Cited by PubMed: 26522624DOI: 10.1021/ACS.JMEDCHEM.5B01343 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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