5FJS

Bacterial beta-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2)

5FJS の概要

• エントリーDOI: 10.2210/pdb5fjs/pdb
• 分子名称: GLUCOSYLCERAMIDASE, CALCIUM ION (3 entities in total)
• 機能のキーワード: hydrolase, bile acid beta-glucosidase, glucosylceramidase, gba2, hereditary ataxia
• 由来する生物種: THERMOANAEROBACTERIUM XYLANOLYTICUM
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 180813.36

構造登録者

Charoenwattanasatien, R.,Pengthaisong, S.,Breen, I.,Mutoha, R.,Sansenya, S.,Hua, Y.,Tankrathok, A.,Wu, L.,Songsiriritthigul, C.,Tanaka, H.,Williams, S.J.,Davies, G.J.,Kurisu, G.,Ketudat Cairns, J.R. (登録日: 2015-10-12, 公開日: 2016-05-11, 最終更新日: 2024-01-10)

• 主引用文献: Charoenwattanasatien, R.,Pengthaisong, S.,Breen, I.,Mutoha, R.,Sansenya, S.,Hua, Y.,Tankrathok, A.,Wu, L.,Songsiriritthigul, C.,Tanaka, H.,Williams, S.J.,Davies, G.J.,Kurisu, G.,Ketudat Cairns, J.R.; Bacterial Beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (Gba2); Acs Chem.Biol., 11:1891-, 2016; PubMed: 27115290; DOI: 10.1021/ACSCHEMBIO.6B00192

実験手法

X-RAY DIFFRACTION (2.6 Å)