5FI3
HETEROYOHIMBINE SYNTHASE THAS1 FROM CATHARANTHUS ROSEUS - COMPLEX WITH NADP+
Summary for 5FI3
Entry DOI | 10.2210/pdb5fi3/pdb |
Descriptor | Tetrahydroalstonine synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION, ... (5 entities in total) |
Functional Keywords | heteroyohimbine synthase, medium chain dehydrogenase/reductase, nadp+ dependent enzyme, zinc binding site, oxidoreductase |
Biological source | Catharanthus roseus (Madagascar periwinkle) |
Total number of polymer chains | 2 |
Total formula weight | 78636.54 |
Authors | Stavrinides, A.,Tatsis, E.C.,Caputi, L.,Foureau, E.,Stevenson, C.E.M.,Lawson, D.M.,Courdavault, V.,O'Connor, S.E. (deposition date: 2015-12-22, release date: 2016-07-27, Last modification date: 2024-05-08) |
Primary citation | Stavrinides, A.,Tatsis, E.C.,Caputi, L.,Foureau, E.,Stevenson, C.E.,Lawson, D.M.,Courdavault, V.,O'Connor, S.E. Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity. Nat Commun, 7:12116-12116, 2016 Cited by PubMed: 27418042DOI: 10.1038/ncomms12116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.05 Å) |
Structure validation
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