5FG6
Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe
Summary for 5FG6
Entry DOI | 10.2210/pdb5fg6/pdb |
Descriptor | Bromodomain-containing protein 1, 1,2-ETHANEDIOL, 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide, ... (6 entities in total) |
Functional Keywords | moz-morf complex, transcription |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : O95696 |
Total number of polymer chains | 1 |
Total formula weight | 15704.27 |
Authors | Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (deposition date: 2015-12-20, release date: 2016-02-03, Last modification date: 2024-01-10) |
Primary citation | Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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