5FG6

Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe

5FG6 の概要

• エントリーDOI: 10.2210/pdb5fg6/pdb
• 分子名称: Bromodomain-containing protein 1, 1,2-ETHANEDIOL, 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide, ... (6 entities in total)
• 機能のキーワード: moz-morf complex, transcription
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : O95696
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15704.27

構造登録者

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (登録日: 2015-12-20, 公開日: 2016-02-03, 最終更新日: 2024-01-10)

• 主引用文献: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe; To Be Published,

実験手法

X-RAY DIFFRACTION (1.1 Å)