5FG5

Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe

5FG5 の概要

• エントリーDOI: 10.2210/pdb5fg5/pdb
• 分子名称: Peregrin, ~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide, NITRATE ION, ... (4 entities in total)
• 機能のキーワード: peregrin, moz-morf complex, transcription
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : P55201
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28230.28

構造登録者

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Brennan, P.E.,Knapp, S. (登録日: 2015-12-20, 公開日: 2015-12-30, 最終更新日: 2024-01-10)

• 主引用文献: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Brennan, P.E.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe; To Be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)