5FDQ
Murine COX-2 S530T mutant
Summary for 5FDQ
Entry DOI | 10.2210/pdb5fdq/pdb |
Related | 5F19 5F1A |
Descriptor | Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | cyclooxygenase, cyxlooxygenase-2, monotopic, cox-2, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 139969.79 |
Authors | Lucido, M.J.,Orlando, B.J.,Malkowski, M.G. (deposition date: 2015-12-16, release date: 2016-03-16, Last modification date: 2024-10-16) |
Primary citation | Lucido, M.J.,Orlando, B.J.,Vecchio, A.J.,Malkowski, M.G. Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry. Biochemistry, 55:1226-1238, 2016 Cited by PubMed: 26859324DOI: 10.1021/acs.biochem.5b01378 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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