5F6E
Crystal Structure of human Ubc9 (K48A/K49A/E54A)
Summary for 5F6E
Entry DOI | 10.2210/pdb5f6e/pdb |
Related | 5F6D 5F6U 5F6V 5F6W 5F6X 5F6Y |
Descriptor | SUMO-conjugating enzyme UBC9, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | ubc9, sumoylation, drug discovery, ligase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: P63279 |
Total number of polymer chains | 1 |
Total formula weight | 17787.44 |
Authors | Lountos, G.T.,Hewitt, W.M.,Zlotkowski, Z.,Dahlhauser, S.,Saunders, L.B.,Needle, D.,Tropea, J.E.,Zhan, C.,Wei, G.,Ma, B.,Nussinov, R.,Schneekloth, J.S.Jr.,Waugh, D.S. (deposition date: 2015-12-05, release date: 2016-04-27, Last modification date: 2023-09-27) |
Primary citation | Hewitt, W.M.,Lountos, G.T.,Zlotkowski, K.,Dahlhauser, S.D.,Saunders, L.B.,Needle, D.,Tropea, J.E.,Zhan, C.,Wei, G.,Ma, B.,Nussinov, R.,Waugh, D.S.,Schneekloth, J.S. Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angew.Chem.Int.Ed.Engl., 55:5703-5707, 2016 Cited by PubMed: 27038327DOI: 10.1002/anie.201511351 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)