5F3J

Crystal structure of DBP in complex with inhibitory monoclonal antibody 2D10

5F3J の概要

• エントリーDOI: 10.2210/pdb5f3j/pdb
• 分子名称: Duffy receptor, Antibody 2D10 single chain variable fragment (2 entities in total)
• 機能のキーワード: plasmodium, vivax, duffy binding protein, dbp, antibody, malaria, scfv, neutralizing, interaction, immune, blocking, invasion, vaccine, therapeutic, immune system
• 由来する生物種: Plasmodium vivax (strain Salvador I); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 139676.00

構造登録者

Chen, E.,Salinas, N.D.,Tolia, N.H. (登録日: 2015-12-02, 公開日: 2016-05-18, 最終更新日: 2023-09-27)

• 主引用文献: Chen, E.,Salinas, N.D.,Huang, Y.,Ntumngia, F.,Plasencia, M.D.,Gross, M.L.,Adams, J.H.,Tolia, N.H.; Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.; Proc.Natl.Acad.Sci.USA, 113:6277-6282, 2016; PubMed: 27194724; DOI: 10.1073/pnas.1600488113

実験手法

X-RAY DIFFRACTION (4.001 Å)