5F34

Crystal structure of membrane associated PatA from Mycobacterium smegmatis in complex with S-hexadecyl Coenzyme A - P21 space group

Summary for 5F34

DescriptorPhosphatidylinositol mannoside acyltransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S})-4-[[3-(2-hexadecylsulfanylethylamino)-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate (3 entities in total)
Functional Keywordsacyltransferase, glycolipid biosynthesis, transferase
Biological sourceMycobacterium smegmatis str. MC2 155
Cellular locationCell membrane ; Single-pass membrane protein  A0QWG5
Total number of polymer chains4
Total molecular weight141162.85
Authors
Albesa-Jove, D.,Svetlikova, Z.,Carreras-Gonzalez, A.,Tersa, M.,Sancho-Vaello, E.,Cifuente, J.O.,Mikusova, K.,Guerin, M.E. (deposition date: 2015-12-02, release date: 2016-03-09, Last modification date: 2016-03-23)
Primary citation
Albesa-Jove, D.,Svetlikova, Z.,Tersa, M.,Sancho-Vaello, E.,Carreras-Gonzalez, A.,Bonnet, P.,Arrasate, P.,Eguskiza, A.,Angala, S.K.,Cifuente, J.O.,Kordulakova, J.,Jackson, M.,Mikusova, K.,Guerin, M.E.
Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Nat Commun, 7:10906-10906, 2016
PubMed: 26965057 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms10906
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.281 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.309202.0%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution