5F34
Crystal structure of membrane associated PatA from Mycobacterium smegmatis in complex with S-hexadecyl Coenzyme A - P21 space group
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008654 | biological_process | phospholipid biosynthetic process |
| A | 0009247 | biological_process | glycolipid biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0046488 | biological_process | phosphatidylinositol metabolic process |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008654 | biological_process | phospholipid biosynthetic process |
| B | 0009247 | biological_process | glycolipid biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0046488 | biological_process | phosphatidylinositol metabolic process |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0008654 | biological_process | phospholipid biosynthetic process |
| C | 0009247 | biological_process | glycolipid biosynthetic process |
| C | 0016020 | cellular_component | membrane |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0046488 | biological_process | phosphatidylinositol metabolic process |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0008654 | biological_process | phospholipid biosynthetic process |
| D | 0009247 | biological_process | glycolipid biosynthetic process |
| D | 0016020 | cellular_component | membrane |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0046488 | biological_process | phosphatidylinositol metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue HD6 A 401 |
| Chain | Residue |
| A | LEU122 |
| A | SER206 |
| A | PRO220 |
| A | GLY222 |
| A | GLU229 |
| A | LEU124 |
| A | TRP130 |
| A | THR146 |
| A | VAL147 |
| A | ARG164 |
| A | PHE182 |
| A | CYS196 |
| A | MET198 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue HD6 B 401 |
| Chain | Residue |
| B | TRP130 |
| B | ALA133 |
| B | GLY134 |
| B | THR146 |
| B | VAL147 |
| B | GLU149 |
| B | ARG164 |
| B | CYS196 |
| B | MET198 |
| B | PRO220 |
| B | GLY222 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue HD6 C 401 |
| Chain | Residue |
| C | LEU124 |
| C | TRP130 |
| C | ALA133 |
| C | GLY134 |
| C | CYS196 |
| C | MET198 |
| C | ASP202 |
| C | PRO220 |
| C | GLY222 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue HD6 D 401 |
| Chain | Residue |
| D | TRP130 |
| D | THR146 |
| D | VAL147 |
| D | GLU149 |
| D | ARG164 |
| D | PHE182 |
| D | CYS196 |
| D | MET198 |
| D | ARG201 |
| D | ASP202 |
| D | PRO220 |
| D | GLY222 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:26965057, ECO:0000305|PubMed:29185694 |
| Chain | Residue | Details |
| A | HIS126 | |
| B | HIS126 | |
| C | HIS126 | |
| D | HIS126 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:26965057, ECO:0000305|PubMed:29185694 |
| Chain | Residue | Details |
| A | GLU200 | |
| B | GLU200 | |
| C | GLU200 | |
| D | GLU200 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:26965057 |
| Chain | Residue | Details |
| A | HIS126 | |
| C | ARG164 | |
| C | SER206 | |
| C | GLU229 | |
| D | HIS126 | |
| D | ARG164 | |
| D | SER206 | |
| D | GLU229 | |
| A | ARG164 | |
| A | SER206 | |
| A | GLU229 | |
| B | HIS126 | |
| B | ARG164 | |
| B | SER206 | |
| B | GLU229 | |
| C | HIS126 |
