5F2U

Structure of Fully modified farnesylated INPP5E Peptide in complex with PDE6D

5F2U の概要

• エントリーDOI: 10.2210/pdb5f2u/pdb
• 分子名称: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, s-farnesyl-l-cysteine methyl ester, FARNESYL, ... (4 entities in total)
• 機能のキーワード: lipid binding protein, immunoglobulin-like, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm, cytosol : O43924
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 36079.52

構造登録者

Fansa, E.K.,Isamil, S.,Wittinghofer, A. (登録日: 2015-12-02, 公開日: 2016-04-13, 最終更新日: 2024-01-10)

• 主引用文献: Fansa, E.K.,Koesling, S.K.,Zent, E.,Wittinghofer, A.,Ismail, S.; PDE6delta-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity.; Nat Commun, 7:11366-, 2016; PubMed: 27063844; DOI: 10.1038/NCOMMS11366

実験手法

X-RAY DIFFRACTION (1.85 Å)