5ERD

Crystal structure of human Desmoglein-2 ectodomain

Summary for 5ERD

Entry DOI	10.2210/pdb5erd/pdb
Related	5EQX 5ERP
Descriptor	Desmoglein-2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	extracellular cadherin domain, cell adhesion, desmosome, cell surface
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	131621.94
Authors	Brasch, J.,Harrison, O.J.,Shapiro, L. (deposition date: 2015-11-13, release date: 2016-06-22, Last modification date: 2023-09-27)
Primary citation	Harrison, O.J.,Brasch, J.,Lasso, G.,Katsamba, P.S.,Ahlsen, G.,Honig, B.,Shapiro, L. Structural basis of adhesive binding by desmocollins and desmogleins. Proc.Natl.Acad.Sci.USA, 113:7160-7165, 2016 Cited by PubMed: 27298358 DOI: 10.1073/pnas.1606272113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation