5EQL
Isoform-specific inhibition of SUMO-dependent protein-protein interactions
Summary for 5EQL
Entry DOI | 10.2210/pdb5eql/pdb |
Descriptor | SUMO-Affirmer-S2D5, Small ubiquitin-related modifier 2 (3 entities in total) |
Functional Keywords | ubiquitin, sumoylation, protein binding |
Biological source | synthetic construct More |
Cellular location | Nucleus: P61956 |
Total number of polymer chains | 2 |
Total formula weight | 22217.25 |
Authors | Hughes, D.J.,Tiede, C.,Hall, N.,Tang, A.A.S.,Trinh, C.H.,Zajac, K.,Mandal, U.,Howell, G.,Edwards, T.A.,McPherson, M.J.,Tomlinson, D.C.,Whitehouse, A. (deposition date: 2015-11-13, release date: 2016-11-23, Last modification date: 2024-01-10) |
Primary citation | Hughes, D.J.,Tiede, C.,Penswick, N.,Tang, A.A.,Trinh, C.H.,Mandal, U.,Zajac, K.Z.,Gaule, T.,Howell, G.,Edwards, T.A.,Duan, J.,Feyfant, E.,McPherson, M.J.,Tomlinson, D.C.,Whitehouse, A. Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology. Sci Signal, 10:-, 2017 Cited by PubMed: 29138295DOI: 10.1126/scisignal.aaj2005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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