5EPI

CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT

This is a non-PDB format compatible entry.

Summary for 5EPI

• Entry DOI: 10.2210/pdb5epi/pdb
• Descriptor: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (4 entities in total)
• Functional Keywords: influenza b virus, rna-dependent rna polymerase, heterotrimer, subunits pa, pb1, pb2, viral rna, crna 5' end, influenza, transferase
• Biological source: Influenza B virus (B/Memphis/13/2003); More
• Total number of polymer chains: 24
• Total formula weight: 1600856.36

Authors

Guilligay, D.,Cusack, S. (deposition date: 2015-11-11, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Thierry, E.,Guilligay, D.,Kosinski, J.,Bock, T.,Gaudon, S.,Round, A.,Pflug, A.,Hengrung, N.,El Omari, K.,Baudin, F.,Hart, D.J.,Beck, M.,Cusack, S.; Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.; Mol.Cell, 61:125-137, 2016; PubMed: 26711008; DOI: 10.1016/j.molcel.2015.11.016

Experimental method

X-RAY DIFFRACTION (4.1 Å)