5EOF
Crystal structure of OPTN NTD and TBK1 CTD complex
Summary for 5EOF
Entry DOI | 10.2210/pdb5eof/pdb |
Related | 5EOA |
Descriptor | Optineurin, Serine/threonine-protein kinase TBK1 (3 entities in total) |
Functional Keywords | optn, tbk1, als, autophagy, protein binding-transferase complex, protein binding/transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, perinuclear region: Q96CV9 Cytoplasm : Q9UHD2 |
Total number of polymer chains | 4 |
Total formula weight | 31796.10 |
Authors | |
Primary citation | Li, F.,Xie, X.,Wang, Y.,Liu, J.,Cheng, X.,Guo, Y.,Gong, Y.,Hu, S.,Pan, L. Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7:12708-12708, 2016 Cited by PubMed: 27620379DOI: 10.1038/ncomms12708 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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