5EN3
Crystal structure of human transthyretin in complex with luteolin-Cl at 1.25 A resolution
Summary for 5EN3
Entry DOI | 10.2210/pdb5en3/pdb |
Related | 4qxv |
Descriptor | Transthyretin, 2-[3,4-bis(oxidanyl)phenyl]-7-chloranyl-5-oxidanyl-chromen-4-one, SODIUM ION, ... (5 entities in total) |
Functional Keywords | beta barrel, wild type human ttr, transthyretin, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28279.17 |
Authors | Begum, A.,Nilsson, L.,Olofsson, A.,Sauer-Eriksson, A.E. (deposition date: 2015-11-09, release date: 2016-04-20, Last modification date: 2024-01-10) |
Primary citation | Nilsson, L.,Larsson, A.,Begum, A.,Iakovleva, I.,Carlsson, M.,Brannstrom, K.,Sauer-Eriksson, A.E.,Olofsson, A. Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity. Plos One, 11:e0153112-e0153112, 2016 Cited by PubMed: 27050398DOI: 10.1371/journal.pone.0153112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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