5EMU
Crystal structure of deoxyribose-phosphate aldolase from Escherichia coli (K58E-Y96W mutant) after acetaldehyde treatment and heating
Summary for 5EMU
Entry DOI | 10.2210/pdb5emu/pdb |
Related | 5eky 5el1 |
Descriptor | Deoxyribose-phosphate aldolase, 1-BUTANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | dera, tim barrel, lyase, suicide inhibitor |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 1 |
Total formula weight | 28933.08 |
Authors | Weiergraeber, O.H.,Dick, M.,Pietruszka, J. (deposition date: 2015-11-06, release date: 2016-05-04, Last modification date: 2024-01-10) |
Primary citation | Dick, M.,Hartmann, R.,Weiergraber, O.H.,Bisterfeld, C.,Classen, T.,Schwarten, M.,Neudecker, P.,Willbold, D.,Pietruszka, J. Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies. Chem Sci, 7:4492-4502, 2016 Cited by PubMed: 30155096DOI: 10.1039/c5sc04574f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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