5EMT

Human Histidine Triad Nucleotide Binding Protein 1 (hHint1)-copper complex

Summary for 5EMT

Entry DOI	10.2210/pdb5emt/pdb
Related	1AV5 1KPA 1KPB 1KPC 1KPE 3TW2
Descriptor	Histidine triad nucleotide-binding protein 1, COPPER (II) ION (3 entities in total)
Functional Keywords	hint, histidine triad, hit, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P49773
Total number of polymer chains	2
Total formula weight	28637.20
Authors	Maize, K.M.,Nix, J.C.,Finzel, B.C. (deposition date: 2015-11-06, release date: 2016-11-09, Last modification date: 2023-09-27)
Primary citation	Shah, R.,Chou, T.F.,Maize, K.M.,Strom, A.,Finzel, B.C.,Wagner, C.R. Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain. Biochem. Biophys. Res. Commun., 491:760-766, 2017 Cited by PubMed: 28739258 DOI: 10.1016/j.bbrc.2017.07.111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation