5EME
Complex of RNA r(GCAGCAGC) with antisense PNA p(CTGCTGC)
Summary for 5EME
Entry DOI | 10.2210/pdb5eme/pdb |
Descriptor | RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3'), Antisense PNA strand, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | cag repeats, rna/pna, pna antisense oligomer, poly-q dieseases, rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 4821.63 |
Authors | Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W. (deposition date: 2015-11-06, release date: 2016-01-13, Last modification date: 2024-01-10) |
Primary citation | Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W. The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs. Nucleic Acids Res., 44:1937-1943, 2016 Cited by PubMed: 26717983DOI: 10.1093/nar/gkv1513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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