5ELJ

Isoform-specific inhibition of SUMO-dependent protein-protein interactions

5ELJ の概要

• エントリーDOI: 10.2210/pdb5elj/pdb
• 分子名称: SUMO-Affirmer-S2D5, Small ubiquitin-related modifier 1 (3 entities in total)
• 機能のキーワード: ubiquitin, sumoylation, signaling protein
• 由来する生物種: synthetic construct; 詳細
• 細胞内の位置: Nucleus membrane: P63165
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22938.19

構造登録者

Hughes, D.J.,Tiede, C.,Hall, N.,Tang, A.A.S.,Trinh, C.H.,Zajac, K.,Mandal, U.,Howell, G.,Edwards, T.A.,McPherson, M.J.,Tomlinson, D.C.,Whitehouse, A. (登録日: 2015-11-04, 公開日: 2016-11-16, 最終更新日: 2024-01-10)

• 主引用文献: Hughes, D.J.,Tiede, C.,Penswick, N.,Tang, A.A.,Trinh, C.H.,Mandal, U.,Zajac, K.Z.,Gaule, T.,Howell, G.,Edwards, T.A.,Duan, J.,Feyfant, E.,McPherson, M.J.,Tomlinson, D.C.,Whitehouse, A.; Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.; Sci Signal, 10:-, 2017; PubMed: 29138295; DOI: 10.1126/scisignal.aaj2005

実験手法

X-RAY DIFFRACTION (1.983 Å)