5ELI
Triggering receptor expressed on myeloid cells 2
Summary for 5ELI
Entry DOI | 10.2210/pdb5eli/pdb |
Descriptor | Triggering receptor expressed on myeloid cells 2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | activating receptors, trem2, innate immunity, immune system receptor, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 28740.40 |
Authors | Brett, T.J.,Kober, D.L. (deposition date: 2015-11-04, release date: 2016-12-28, Last modification date: 2023-09-27) |
Primary citation | Kober, D.L.,Alexander-Brett, J.M.,Karch, C.M.,Cruchaga, C.,Colonna, M.,Holtzman, M.J.,Brett, T.J. Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. Elife, 5:-, 2016 Cited by PubMed: 27995897DOI: 10.7554/eLife.20391 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.0977 Å) |
Structure validation
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