5EIJ
Carbonic Anhydrase II in complex with Sulfonamide Inhibitor
Summary for 5EIJ
| Entry DOI | 10.2210/pdb5eij/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 1-(3-iodanylphenyl)-3-(4-sulfamoylphenyl)thiourea, ... (6 entities in total) |
| Functional Keywords | sulfonamide, inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29771.79 |
| Authors | Lomelino, C.L.,Mahon, B.P.,McKenna, R. (deposition date: 2015-10-29, release date: 2016-11-09, Last modification date: 2023-09-27) |
| Primary citation | Lomelino, C.L.,Mahon, B.P.,McKenna, R.,Carta, F.,Supuran, C.T. Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111. Bioorg. Med. Chem., 24:976-981, 2016 Cited by PubMed: 26810836DOI: 10.1016/j.bmc.2016.01.019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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