5EHV

human carbonic anhydrase II in complex with ligand

Summary for 5EHV

Entry DOI	10.2210/pdb5ehv/pdb
Related	5EH5 5EH7 5EH8 5EHW 5FLO 5FLP 5FLQ 5FLR 5FLS 5FLT 5FNG 5FNH 5FNI 5FNJ 5FNK 5FNM
Descriptor	Carbonic anhydrase 2, (~{E})-3-[3-[[3-(2-hydroxy-2-oxoethyl)phenyl]methoxy]phenyl]prop-2-enoic acid, ZINC ION, ... (7 entities in total)
Functional Keywords	human carbonic anhydrase ii, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29827.90
Authors	Ren, B. (deposition date: 2015-10-29, release date: 2016-03-09, Last modification date: 2024-03-06)
Primary citation	Woods, L.A.,Dolezal, O.,Ren, B.,Ryan, J.H.,Peat, T.S.,Poulsen, S.A. Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59:2192-2204, 2016 Cited by PubMed: 26882437 DOI: 10.1021/acs.jmedchem.5b01940 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.208 Å)

Structure validation